Profile for Associate Professor Joanne Jamie

Research Interests

Bio-organic and medicinal chemistry

• Working in partnership with Indigenous people on traditional medicinal plant knowledge for cultural preservation and drug discovery.
• Understanding the structure, function and inhibition of the medicinally important human enzyme indoleamine 2,3-dioxygenase to rationally develop potent inhibitors.
• Understanding age-related nuclear cataract and human lens chemistry using synthesis and biological models.

Chemical education

• Exploring the Indigenous Science Education Program to understand the key factors for effective engagement of Indigenous students in science.

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Selected Publications

1. J Gaikwad, V Khanna, S Vemulpad, J Jamie, J Kohen, S Ranganathan, “CMKb: a Web Based Prototype for Integrating Australian Aboriginal Customary Medicinal Plant Knowledge”. BMC Bioinformatics, 2008, 9, S25-33.  
2. S Vemulpad, J Jamie, “Partnerships in Traditional Medicinal Plant Research”. Issues, 2008, 84, 45-48..
3. J Mizdrak, P Hains, R Truscott, J Jamie, M Davies, “Tryptophan-Derived Ultraviolet Filter Compounds Covalently Bound to Lens Proteins are Photosensitisers of Oxidative Damage”, Free Radical Biology & Medicine, 2008, 44, 1108-1119.
4. C Austin, F Astelbauer, P Kosim-Satyaputra, H Ball, R Willows, J Jamie, N Hunt, “Mouse and Human Indoleamine 2,3-Dioxygenase Display Some Direct Biochemical and Structural Properties”, Amino Acids, 2008, 99-106.
5. J Mizdrak, PG Hains, RJW Truscott, MJ Davies, JF Jamie, “Novel Human Lens Metabolite from Normal Cataractous Human Lenses”, Tetrahedron, 2007, 63, 4990-4999. 
6. Q Liu, D Harrington, JL Kohen, S Vemulpad, JF Jamie, “Bactericidal and Cyclooxygenase Inhibitory Diterpenes from Eremophila sturtii”, Phytochemistry, 2006, 67, 1256-1261. 
7. A Matin, IM Streete, IM Jamie, RJW Truscott, JF Jamie, “A Fluorescence-Based Assay for Indoleamine 2,3-Dioxygenase”, Analytical Biochemistry, 2006, 349, 96-102.
8. N Brouwer, J Kohen, J., J Jamie, S Vemulpad, “Modification of the Fluorescein Diacetate Assay for Screening of Antifungal Agents Against Candida albicans: Comparison with the NCCLS methods”, Journal of Microbiological Methods, 2006, 66, 234-241.
9. S Wanandy, N Brouwer, Q Liu, A Mahon, S Cork, P Karuso, S Vemulpad, J Jamie, “Optimisation of the Fluorescein Diacetate Antibacterial Assay”, Journal of Microbiological Methods, 2005, 60, 21-30.
10. N Brouwer, Q Liu, D Harrington, J Kohen, S Vemulpad, J Jamie, M Randall, D Randall, “An Ethnopharmacological Study of Medicinal Plants in New South Wales”, Molecules, 2005, 10, 1252-1262.
11. NR Parker, JF Jamie, MJ Davies, RJW Truscott, “Protein-Bound Kynurenine is a Photosensitiser of Oxidative Damage”, Free Radical Biology and Medicine, 2004, 37, 1479-1489.
12. C Austin, J Mizdrak, A Matin, N Sirijovski, P Kosim-Satyaputra, R Willows, T Roberts, R Truscott, G Polekhina, M Parker, J Jamie, “Optimised Expression and Purification of Human Indoleamine 2,3-Dioxygenase”. Protein Expression and Purification, 2004, 37, 392-398.

Awards and Distinctions

• 2008 Macquarie University Vice Chancellor’s Award for Teaching Excellence
  
• 2008 Finalist, Eureka Prize for Promoting Understanding of Science
  
• 2008 Macquarie University Community Engagement Award for the Indigenous Science Education Program
  
• 2007 Macquarie University Innovation in Partnership Award for the Indigenous Science Education Program
  
• 2007 Finalist, Eureka Prize for Promoting Understanding of Science
  
• Fellow of the Royal Australian Chemical Institute (FRACI) 2006
  
• The Royal Australian Chemical Institute (RACI) 2002 Centenary of Federation Teaching Awards in Chemistry, Tertiary
  
• 2001 RACI NSW Branch President’s Award

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Contact Details

Contact Details

Links to Other pages

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